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Methamphetamine is different from some of the street drugs in that it is manufactured and not cultivated. It is a particularly dangerous drug because of its highly addictive nature. In fact, it is one of the very most addictive drugs on the street. It is usually produced and distributed as an odorless powder which can range from white to pink to brown.
Meth is largely categorized as a stimulant. It was originally developed as a treatment for nasal congestion. Not surprisingly, many users experience nasal and mucosal dryness while using and rebound excessive nasal discharge and sweating when withdrawing. The other effects of meth can be described as anorexic, hallucinogenic, and also as causing insomnia.
Fundamentally, methamphetamine carries out its effects in the brain itself. At critical junctions between neurons (synapses) meth is incorporated in such a way to increase the free concentration of epinephrine, norepinephrine, dopamine, and serotonin inside the cell until it begins to leak out. Furthermore, the breakdown of these spilled contents by an enzyme COMT is quickly saturated. This leakage of these important neurotransmitters over activates these neurons causing a stimulant surge as well as the other associated effects like hallucinations.
Because of the flood of stimulant effects, many meth users will have a rapid pulse and high blood pressure. Many even present to the ER complaining of chest pain, and of those that do as many as 25% are diagnosed with acute coronary syndrome (ACS) a potentially life threatening heart condition1. Users often become malnourished-looking and agitated when intoxicated. Hyperthermia can also result in acute intoxication. The drug can also cause users to become violent and aggressive.
Meth is a particularly dangerous drug in pregnancy. It is associated with numerous birth defects as well as growth restriction of the fetus and dangerous problems with the placenta. Methamphetamine is also passed into breast milk.
Ultimately, it is important to maintain a healthy respect for methamphetamine. It is a powerfully addictive drug that is particularly dangerous to its users. Meth can cause damage the body quickly and ravish the lives of its users. Overcoming meth should not be attempted alone. Anyone affected by methamphetamine should seek professional help including rehab and group counseling.
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